Quarantined American Brings Home Reality of Deadliest Microbe

Avian flu and SARS made scary news for Americans, but the risk remains theoretical. Now, with famed TB patient Andrew Speaker scheduled for lung resection, witness the grim reality of tuberculosis. The world’s deadliest microbe is defeating the magic bullet.

About one third of people in the world are infected (most in developing countries). Now the extremely resistant form of Mycobacterium tuberculosis has sent a healthy, young, jet-setting American lawyer into confinement.

Recognized only two years ago and defined in detail last year, extremely drug resistant tuberculosis (XDR-TB) defies both first-line and second-line antibiotic treatment.

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The threat of XDR-TB is especially grave among HIV-infected patients.

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