A report in JNCI unveils a model of breast-cancer risk assessment created specifically for African-American women. Based in part on data from the Women’s Contraceptive and Reproductive Experience (CARE) study, the new CARE model shows that 30% of African-American women should have qualified for the STAR trial of breast cancer prevention. That protocol used the standard NCI Breast Cancer Risk Assessment Tool (BRCAT), which judged only 15% eligible.
The new tool is not recommended for women who have BRCA mutations or a history of breast cancer.
Last July, Howard University researchers reported that a modified version of the BCRAT (or Gail model) was even worse at predicting risk in this population than the original Gail model itself.
A meta-analysis in JCO last year revealed that African-Americans have poorer outcomes from breast cancer treatment irrespective of socioeconomic factors. Risk counseling based on erroneous assessment must be among the reasons.
See what else you can find in the categories that sort your results by document type:
Clinical Trials for Patients
Learn more about the CARE study assessing breast cancer risk among white and African American women.
Practical Articles and News
Locate the Gail model itself on the National Cancer Institute website. (The new CARE model isn’t there yet. The NCI says it will be there shortly.)
Posted by Cranky Aged Mama
Posted by Cranky Aged Mama
