Multicenter trial defines predictors of heart failure admission, death
Renal failure and pneumonia are the most deadly comorbidities for heart-failure patients, either in the hospital or within 3 months post-discharge. These results come from OPTIMIZE-HF, the first large multicenter trial to pre-define predictors and outcomes in heart failure
Pneumonia, ischemia and arrhythmia were the most frequent factors precipitating hospital admission. Uncontrolled hypertension and nonadherence to diet or medication were less adverse factors.
Practice Guidelines
The report bolsters national heart failure guidelines that call for detecting and addressing precipitating factors in acute decompensated heart failure.
Clinical Trials
A description of OPTIMIZE-HF (and a complete clickable list of its related publications), is available from the government Clinical Trials directory available on SearchMedica category.
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