Antiplatelet drug with on-off switch

An investigational treatment for acute coronary syndrome that reduces major cardiovascular events more effectively and quickly than available drugs without increasing overall bleeding was announced at the European Society of Cardiology meeting. Its antiplatelet effects are readily reversible.

Someone found news reports about it by searching on the drug name.

Search term: Brilinta

RESULT: ESC: Reversible Antiplatelet Promising for ACS
MedPage Today

News reports mentioned the name of the first author, which provided an easy way to find the study report in the New England Journal of Medicine.

Search term: Wallentin

RESULT: Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes
New England Journal of Medicine

These results came from the randomized PLATO trial that compared the investigational drug with clopidogrel.

You can find the description of that study in the Clinical Trials article category.

Search term: PLATO

RESULT: A Comparison of AZD6140 and Clopidogrel in Patients With Acute Coronary Syndrome (PLATO)
ClinicalTrials.gov

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OTHER RECENT SEARCHES

Search termdeficiency “vitamin C”

RESULT: Vitamin C Deficiency in a Population of Young Canadian Adults
American Journal of Epidemiology

Many young Canadians have vitamin C deficiency due to their diet. Those who have vitamin C deficiency are also more likely to have health risks such as obesity and high blood pressure.

(Full text of this article is available online.)

Search termconfidentiality law

RESULT: A Physician’s Duty to Warn Third Parties of Hereditary Risk
AMA Virtual Mentor

When is it your responsibility to notify blood relatives of results from your patient’s genetic testing that might have implications for their own health?

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NOTEWORTHY SEARCH OF THE WEEK

Search term immune reconstitution inflammatory syndromes what’s new

RESULT: New guidelines for treatment of HIV-associated opportunistic infections in children published
Pediatrics Supersite

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SEARCH TIP: Finding the latest information

The words “what’s new” in this search term will not have the desired effect, unless they happen to appear in the article title or high in the text.

The result shown here actually is among the latest information on this topic, but the words “what’s new” in the search term aren’t responsible for that. The word “what’s” appears somewhere in the article text, as we can see from the blurb beneath the results link, showing that it figured in the rank of this result. But its context has nothing to do with the news.

This article appears high on the results list because is publication date is recent. Default results on SearchMedica are prioritized by publication date, with the most recent (and most relevant) at the top of the list.

The best way to learn what’s new is simply to type a topic into the search box and look at the first few results.

If an old article has “what’s new” in its headline, putting those words in the query will have the ironic effect of delivering an old article when you requested the latest one.

One Response to “Antiplatelet drug with on-off switch”

  1. The Best And Worst Acne Prescription Medications | Free Prescription Medications Says:

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