U.S. shows dramatic rise in VTE among children

Confirming the observations of individual pediatric hematologists, a study of records from tertiary care pediatrics hospitals shows a 70% increase in the number of children in whom venous thromboembolism (VTE) was diagnosed over 7 years. How much of this is because of greater vigilance and better detection? Whatever the situation, the article makes an urgent appeal for VTE guidelines that apply to children, not adults.

RESULT: Dramatic Increase in Venous Thromboembolism in Children’s Hospitals in the United States From 2001 to 2007
Pediatrics | Oct 1, 2009

A child presents with headache and vomiting. Is it cerebral VTE? Diagnosis and treatment are challenging. This series report from a pediatric neurology center in the U.K. discusses presenting features and the results of thrombolytic treatment.

RESULT: Cerebral venous sinus thrombosis: a case series including thrombolysis
Archives of Disease in Childhood | Oct 1, 2009

Search: thrombosis child

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OTHER RECENT SEARCHES ON SEARCHMEDICA

Search: sepsis associated delirium

RESULT: Gaps in patient care practices to prevent hospital-acquired delirium
Canadian Family Physician | Oct 1, 2009

Doctors in the Canadian province of Alberta took a close look at what could be done to prevent dementia from developing in older people who are hospitalized—a common and often deadly problem attributable to both hospital and patient factors. The study found numerous gaps in practice that could reduce hospital-associated dementia, potentially saving both cost and lives.

Search: RA

RESULT: RA therapies in 2009: The latest on drug effectiveness
Journal of Musculoskeletal Medicine | Oct 1, 2009

Recent trials have led to a consensus that rheumatoid arthritis (RA) should be treated early and aggressively. But how? Use of drug combinations is increasing, and there are many new medications. This article reviews the efficacy and safety of new therapies for RA.

RESULT: Rheumatoid arthritis in elderly patients
Geriatrics | Sep 15, 2009

Diagnosing and treating RA in older patients is even more of a challenge; advanced age and comorbidities change the results of diagnostic tests for RA and complicate treatment. This article is a detailed overview of considerations in differential diagnosis and drug therapy, taking special note of the effects of newer medications in this patient group.

Search: trial study pediatrics influenza antivirals

RESULT: Pandemic influenza planning: Addressing the needs of children
American Journal of Public Health | Oct 1, 2009

This search was intended to find either a clinical trial involving children with influenza or a report about such a trial. It was a valiant effort that fell flat, bringing up an essay intended for public health specialists. What went wrong?

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SEARCH TIP: Power searching on SearchMedica

1. Put your topic (influenza, antivirals) first in the search term, not last. Add modifiers or qualifiers (pediatric, trial, study) after the words describing your main topic.

2. To limit your search to a specialty, choose the most appropriate tab from the list above the search box (e.g., Pediatrics).

3. To target a particular type of article, use the article categories (Research/Reviews, Clinical Trials) rather than adding article-type descriptors (trial, study) to the query.

Here’s what you find with the query influenza antivirals children, using the Pediatrics tab and the article category Research/Reviews:

RESULT: Neuraminidase inhibitors for treatment and prophylaxis of influenza in children: systematic review and meta-analysis of randomized controlled trials
British Medical Journal | Aug 11, 2009

Looking for a clinical trial in which to enroll a child who has influenza? Try influenza antivirals children in the Clinical Trials category.

RESULT: Oseltamivir Treatment for Children Less Than 24 Months of Age With Influenza
ClinicalTrials.gov | Sep 10, 2009

(In both cases, we added the modifier “children” to eliminate studies that focus on adults, because the major journals and other websites in the Pediatrics category do include information about adults as well as children.)

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