Can kids be bipolar–and outgrow it?

October 21, 2008

Longitudinal study documents persistence of child bipolar to adulthood

Not only does bipolar I disorder in fact affect children (despite the skeptics), those who have it are at least 13 times as likely as others to experience the disorder as adults, according to the first major prospective study of the question. The report appears in the October Archives of General Psychiatry.

The study followed 115 children enrolled since 1995. At least half are now 18.

More than 44% continued to have manic episodes as adults, and 35% had substance use disorders. Long episode duration and daily cycling were characteristic features of the syndrome in childhood and often continued after age 18.

Young age at onset and having a mother who wasn’t very warm strongly predicted quicker relapse after recovery. Maternal warmth is a known factor from previous studies of bipolar.

Related searches

Treatment of Early Age Mania study

WASH-U-KSADS


Chelation and autism: End of the line?

October 7, 2008

NIMH pulls the plug on chelation therapy trial for autism

A clinical trial of chelation therapy in autistic children with detectable blood levels of mercury has been cancelled by the NIMH.

The agency explained that a suggested link between mercury-containing vaccines and autism has not been proven.

Also, rat studies suggested that chelation therapy might be dangerous in the absence of blood lead.

No children had been enrolled in the clinical trial before it was cancelled.

All of Medicine tab

This month’s edition of Archives of Disease in Childhood compiles a recent study finding no link between the MMR vaccine and autism with letters responding to that study.

Practical Articles/News

A recent article in Psychiatric Times reviews complementary therapies for autism.

Evidence-based Medicine

Placebo worked just as well as chelation therapy in reducing distress among people concerned about the mercury in their dental fillings, according to an old randomized study found in this article category.

(The chelating drug did elute mercury, but people on placebo scored equally on anxiety and somatization measures after treatment.)


Flu shots, cradle to college

October 7, 2008

CDC says far too few tots get influenza vaccine, urges shots from 6 months

All children older than six months should get the flu shot, according to a new advisory from the Centers for Disease Control and Prevention.

Infants between six and 23 months old are at particular risk of hospitalization with influenza. Yet last year only one in five tots in this age range received the influenza vaccine.

The agency is paving the way for your conversation with parents, using a major mass media campaign that targets consumer health blogs and parenting websites.

Twenty two leading agencies, including the American Academy of Family Physicians and the American Academy of Pediatrics, joined last month in a new alliance to bolster public confidence in immunization.

Infants younger than six months can be protected from influenza if the expectant mother gets a flu shot, according to a new study in the New England Journal of Medicine.

Practice Guidelines

Quickly find the latest guidelines on prevention and treatment of influenza in children.

Patient Education

Here’s the place to find reliable information for parents on the question of preventing and treating flu in their kids.


Foreign travelers: bad influence on some kids

September 2, 2008

CDC reports highest measles rates for more than a decade

Measles cases in the US this year are at their highest in more than a decade, as the Centers for Disease Control and Prevention (CDC) reports in Morbidity and Mortality Weekly Reports. In 2000, the CDC declared the disease eradicated in the US.

The increase was due not to people catching measles abroad but largely to unvaccinated children catching it from those who carried the infection from outside the US.

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(Source: Centers for Disease Control and Prevention)

States with more lenient vaccine exemption policies have increased infection rates, according to a recent report in the Journal of the American Medical Association.

Patient Education

Look in this category (in the list above the main search results) for take-home information for parents about measles.

Practice Management

This tab (above the search box) offers practical information about what to do when patients (or their parents) refuse immunization.


How not to eat your way to diabetes

August 12, 2008

Calories—not sugar, carbs, or fat—cause type 2 diabetes in those at risk

What people eat controls what they weigh, and that (setting aside genes and exercise) seems to determine the risk of type 2 diabetes—not the types of macronutrients themselves. That’s the upshot of two new studies in the Archives of Internal Medicine, according to a review in the same issue.

It’s not the sugar in soft drinks or juices but the poundage they so easily add that predisposes to type 2 diabetes, according to a study of young African-American women in the July 28 issue of Archives.

It was probably weight loss per se, not the low-fat or high-fiber diet, that reduced glycemia among postmenopausal women in the other study.

Which is best for weight loss: low carbs, low fat, or the Mediterranean diet? Depends on the patient’s underlying risk profile. The latter may be best for people at risk of diabetes, according to another new report, this one in the New England Journal of Medicine.

Related searches

Mediterranean diet diabetes

obesity children juice

menopause metabolic syndrome testosterone

Research/Reviews

How much exercise do patients need to maintain weight loss? Find more new reports in this article category.

Patient Education

Look in this category for trustworthy information for patients about physical activity and diabetes.


Losing strategy: Purge, don’t binge

June 24, 2008

To create an eating-disordered teen: Turn on MTV, then call her chubby

The largest, longest-running study of disordered eating among adolescents and teenagers shows that about 10% of girls and 3% of boys binge eat, purge, or both at least weekly in order to lose weight. Data come from about 11,000 children of women in the national Nurses Health Study II.

A large group of girls who purge without binge eating are going unrecognized, the authors suggest, because they don’t fit current diagnostic criteria.

The study set out to define predictors of disordered eating. These include
* teasing about weight,
* maternal history of eating disorder (but only for adolescent girls), and
* also for girls, wanting to look like young women in the media.

They urge that young women at risk should be educated about issues of media and body image.

Related Searches

bulimia nervosa

binge eating disorder

Research/Reviews
The results show that adolescent girls are at greater risk if their mothers were affected. What is the evidence about heritability of eating disorders?

Evidence-based Articles
The new study adds to already solid evidence that teasing about weight breeds eating disorders and other emotional problems.


Totally awesome!!!! (But is it oozing?)

June 24, 2008

Increase in body piercings causes headaches for health providers

Doctors should prepare for the consequences as piercing of body parts other than earlobes gains in popularity, according to a government-sponsored study in the UK.

About one in ten adults has had something other than an earlobe or two pierced, the study found. Navels were the most common site (reported by one teen girl in three, with complications in one-third of those cases). Oral piercings are on the increase.

A startling one piercing in ten took place outside a specialist piercing shop. There was at least one report of piercing by self or a friend for every body part mentioned in the study, including nipples and genitals.

One body piercing in 100 ended in hospitalization.

These data confirm and expand on similar results from the United States.

Related searches

auricular perichondritis

tattoos

Research/Reviews

There are numerous reports about the risks that body piercing may cause viral hepatitis.


SSRI Rxs for youth drop. Suicides rise. Coincidence?

October 1, 2007

Close on the heels of news from the CDC that youth suicides are up for the first time in 15 years come the results of a new study that explicitly links this increase with a decline in antidepressant prescriptions.

After the FDA and European authorities issued warnings that blamed SSRIs for suicidal thoughts, a multicenter team tracked SSRI prescriptions for adolescents and children with corresponding suicide rates in both the Netherlands and the U.S.

“If the intent of the pediatric black box warning was to save lives, the warning failed,” the authors contend. Suicide rates in both countries rose afterwards—and most obviously among children and adolescents, whose antidepressant use dropped sharply.

The FDA based its decision on a meta-analysis of studies involving non-fatal suicide attempts. Did this overlook a much higher rate of completions among kids not taking part in clinical trials?

A recent re-analysis of the same data found the suicide risk much lower for children taking SSRIs.

Clinically Useful Categories

Practice Guidelines
Authors of the new study suggest that better education of clinicians would be preferable to hasty black box warnings. Review current guidelines about treating depressed adolescents.

Clinical Trials for Patients
Find clinical trials that may offer the safest way to try antidepressants for adolescents in the current situation.


Study Reveals ADHD Underdiagnosed in Girls

September 17, 2007

A nationwide study has shown that ADHD is under-diagnosed in girls. The researchers used a DSM-based instrument to interview caregivers of children already participating in the large National Health and Nutrition Examination survey.

African-Americans were no more likely to have ADHD than non-Hispanic whites. ADHD was less common among Mexican-Americans (in the first large-scale assessment of this ethnic group).

Previous research reveals that girls show more and different consequences of ADHD than boys, and these persist.

Research Reviews and Editorials
A recent review suggests that ADHD treatments work equally well in girls as in boys.