Chelation and autism: End of the line?

October 7, 2008

NIMH pulls the plug on chelation therapy trial for autism

A clinical trial of chelation therapy in autistic children with detectable blood levels of mercury has been cancelled by the NIMH.

The agency explained that a suggested link between mercury-containing vaccines and autism has not been proven.

Also, rat studies suggested that chelation therapy might be dangerous in the absence of blood lead.

No children had been enrolled in the clinical trial before it was cancelled.

All of Medicine tab

This month’s edition of Archives of Disease in Childhood compiles a recent study finding no link between the MMR vaccine and autism with letters responding to that study.

Practical Articles/News

A recent article in Psychiatric Times reviews complementary therapies for autism.

Evidence-based Medicine

Placebo worked just as well as chelation therapy in reducing distress among people concerned about the mercury in their dental fillings, according to an old randomized study found in this article category.

(The chelating drug did elute mercury, but people on placebo scored equally on anxiety and somatization measures after treatment.)


Foreign travelers: bad influence on some kids

September 2, 2008

CDC reports highest measles rates for more than a decade

Measles cases in the US this year are at their highest in more than a decade, as the Centers for Disease Control and Prevention (CDC) reports in Morbidity and Mortality Weekly Reports. In 2000, the CDC declared the disease eradicated in the US.

The increase was due not to people catching measles abroad but largely to unvaccinated children catching it from those who carried the infection from outside the US.

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(Source: Centers for Disease Control and Prevention)

States with more lenient vaccine exemption policies have increased infection rates, according to a recent report in the Journal of the American Medical Association.

Patient Education

Look in this category (in the list above the main search results) for take-home information for parents about measles.

Practice Management

This tab (above the search box) offers practical information about what to do when patients (or their parents) refuse immunization.


Most Kids Well-Immunized When They Start School, Not at Graduation

September 13, 2007

The CDC has results from its first national survey of adolescent immunizations. While 80% have had the updated measles, mumps, and rubella booster for teens, only 12% are getting the new meningococcal conjugate vaccine.

A different survey shows that more than three in four younger children are getting all their vaccines as recommended. This varies by locale: In Boston, the rate is 84%.

A study published last March suggests that family doctors are not at fault for low teen vaccination rates. During adolescence, visits for preventative care decline sharply. While older teen girls visit gynecologists; older boys just stop going. The authors counsel providing the final scheduled vaccinations during the early teen years.

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Patient Education Materials
Find good information for parents about the meningitis vaccines for teenagers.

Practice Guidelines
Fish out the latest recommended immunization schedule for adolescents (and plan to beat those deadlines).